Amoebiasis: Pharmacotherapy - Pharmacology

Amoebiasis: Pharmacotherapy & Classification of amebicidal agents - Pharmacology The video discusses the pharmacotherapy of amebiasis and classifies the therapeutic agents into three categories: luminal amebicides, systemic amebicides, and mixed amebicides. The video begins by highlighting the importance of luminal amebicides in eradicating asymptomatic colonization of trophozoites in the intestinal lumen, which is necessary to prevent the recurrence of the disease. The luminal amebicides discussed in the video are iodoquinol, diloxanide furoate, and paromomycin, with paromomycin being the most effective agent in this class. The video then moves on to systemic amebicides, which are effective against the amoebas in the intestinal wall and liver. Chloroquine and Dehydroemetine are discussed in this category, with Chloroquine being the most widely used agent and effective against a hepatic abscess but not useful for luminal amoebiasis. Dehydroemetine has some toxicities that limit its use, and the intramuscular form is preferred over the oral form. Finally, the video discusses mixed amebicides, which are effective against both systemic and luminal amoebas. Metronidazole, widely known as Flagyl, is the mixed amebicide of choice for treating amebic infections and is also used to treat other diseases caused by other protozoans and anaerobic bacteria. Tinidazole is another agent in this class, similar to metronidazole in the spectrum of activity and adverse effects. Overall, the video provides a detailed overview of the pharmacotherapy of amebiasis, including the classification of different agents and their modes of action. Thanks for watching & do support us. COVERED TOPICS 0:00 Intro 0:10 Diagram from previous video (amoebiasis) 0:25 Classification of amoebicidal agents 0:40 Luminal amoebicides 2:10 Systemic amoebicides 3:20 Mixed amoebicides 4:10 End LINKS: Also, watch Amoebiasis: Life cycle, Types & Pharmacotherapy - Pharmacology https://youtu.be/-n80uxtD8KA Parasympathomimetics: Clinical Uses & Classification of Direct Acting Cholinergic Drugs https://youtu.be/Uhp_GivuSQg Cholinergic Drugs: Pharmacological actions of Parasympathomimetics, Direct acting drugs https://youtu.be/XxeitbKE68w Cholinergic drugs | Parasympathomimetics classification and mechanism of action - Pharmacology https://youtu.be/0ylQGye76xc Cholinergic transmission | acetylcholine synthesis & metabolism | cholinergic drugs | pharmacology https://youtu.be/PBsCl95X3DI Support us on: Facebook https://web.facebook.com/MK-MediGuide-Lectures-103055758022942/?view_public_for=103055758022942 #MKMediguide #mediguide #amoebiasis #amebiasis #entameba #amebicdysentry #ameba #amoeba